Discover games similar to The Binding of Isaac: Rebirth, and find your next adventure.
The Binding of Isaac: Rebirth is Nicalis's remake of Edmund McMillen's roguelike dungeon crawler, where Isaac fights his way through randomized, Zelda-style basement rooms using tears as his main weapon and a huge pool of strange, often gross item pickups to build a run around. Every run restarts the layout and your items from scratch, so no two basements play the same. We like it for how one weird item combo can completely rewrite how a run feels.
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Shares roguelike, action roguelike and replay value with a similar overall feel.
100%
match
Built around action roguelike, roguelike and replay value, much like the game you started from.
91%
match
Leans on action roguelike, roguelike and dungeon crawler — the same pull that makes the original click.
85%
match
Dungreed shares Isaac's randomized dungeon runs and item-hunting loop, with side-scrolling action and local co-op for a friend to join the run.
Its side-scrolling platforming and skill-tree progression between runs give it a different rhythm than Isaac's top-down rooms.
Brings action roguelike, roguelike and dungeon crawler to the table, with its own spin.
80%
match
Shares action roguelike, roguelike and pixel graphics with a similar overall feel.
80%
match
The original Risk of Rain pairs Isaac's item-stacking, run-based structure with a difficulty that climbs the longer you take, pushing you to balance greed against survival.
Its 2D side-scrolling action and escalating time pressure are a different kind of tension than Isaac's room-by-room exploration.
Built around action roguelike, roguelike and replay value, much like the game you started from.
78%
match
Spelunky applies the same permadeath, randomized-room philosophy to platforming instead of top-down shooting, turning traps, gold and fragile health into Isaac-style tension.
Its platforming-focused physics and lack of a shooting-based item system make the moment-to-moment challenge quite different from Isaac's rooms.
Leans on action roguelike, roguelike and difficult — the same pull that makes the original click.
75%
match
Nuclear Throne keeps Isaac's run-based, item-driven structure but speeds everything up into fast, twin-stick combat through a mutated post-apocalyptic wasteland.
Its faster pace and smaller item pool make each run shorter and punchier than Isaac's slower, puzzle-like room exploration.
Brings action roguelike, replay value and roguelite to the table, with its own spin.
73%
match
Shares action roguelike, roguelike and replay value with a similar overall feel.
73%
match
Built around action roguelike, roguelike and replay value, much like the game you started from.
72%
match
Caveblazers brings the same roguelike, permadeath structure to a platforming cave-crawl, with local co-op for tackling runs alongside a friend.
Its side-scrolling platforming and local co-op option are a different shape than Isaac's single-player, top-down rooms.
We look for games that share something worth loving about The Binding of Isaac: Rebirth. The match score compares game data and is relative to the closest match in this list. Our picks below add our own perspective: why each game appeals to us, who it suits, and where it takes a different path.
Our picks, beyond the numbers
The Binding of Isaac: Rebirth makes each run a fresh experiment: which items you find shape what the rest of the run even feels like, and a lucky combination can turn Isaac into something completely different from the character you started with. We picked games that keep that same thrill of discovery and uncomfortable surprise, even where the genre shifts considerably.
A couple of these are close cousins in structure and tone; others take the item-combination idea somewhere faster, slower, or more narrative. Here's where we'd send an Isaac player next.
For dodging through bullet-filled rooms
Enter the Gungeon combines dungeon runs with a huge arsenal of guns and a dodge-roll that's as important as any weapon. Like Isaac, every run is built from randomized rooms and items, and a good early pickup can define how the rest of the run plays out.
We'd start here for a player who wants Isaac's run structure and item variety but with more emphasis on precise, bullet-hell-style movement and a lighter, more comedic tone.
Its gun-themed humor and bullet-pattern-heavy combat feel quite different from Isaac's unsettling, body-horror visuals and darker themes — expect a sillier, more arcade-focused version of the same basic loop.
For a faster trip through danger
Nuclear Throne offers rapid, top-down action with mutated characters and constantly changing weapon pickups in a post-apocalyptic wasteland. Runs are shorter and more frantic than Isaac's, with less room to plan and more need to react.
We like it for players who want the next attempt to arrive quickly — less time spent per run means more attempts per session, and the pace rewards quick decisions over careful hoarding.
Its post-apocalyptic tone and character-based mutant cast differ from Isaac's basement-and-bible-horror theme, and runs end faster, for better or worse. Choose this when speed matters more to you than Isaac's slower, more methodical pacing.
For runs with a story between them
Hades pairs action roguelike runs with a cast of characters and conversations that develop every time you return to the House of Hades, giving failed attempts an ongoing narrative purpose that Isaac doesn't really offer.
It's our pick when you want a much stronger narrative thread running alongside the item-and-ability experimentation — the story actually rewards repeated attempts rather than treating them as pure practice.
Its mythology, weapon-and-boon system and hand-drawn presentation give it a very different mood from Isaac's grim, surreal tone, and there's a fixed protagonist rather than Isaac's roster of unlockable characters.
For action from the side
Dead Cells offers changing weapons and routes in a fast, side-scrolling world, where a new item can shift your whole approach to a level the same way a strong pickup reshapes a run in Isaac.
We'd choose it for someone who enjoys experimenting with a new build each run, but wants that experimentation paired with platforming and movement rather than Isaac's top-down, room-by-room structure.
Its side-scrolling platforming and real-time combat differ substantially from Isaac's top-down rooms and shooting — the physical feel of playing is a genuinely different experience, even with a similar underlying philosophy about runs and items.
For building chaos with friends
Risk of Rain 2 lets items accumulate visibly on your character as a run goes on, with enemies scaling up in danger the longer you take — tension that builds the same way Isaac's item stacking can turn a run into something unrecognizable by the end.
We like it for the unpredictable ways a run can develop, especially with up to three friends in online co-op piling items onto each other and watching the chaos compound.
Its 3D, third-person perspective and online co-op support are a real departure from Isaac's solitary, top-down runs, and its sci-fi setting swaps out Isaac's basement horror entirely. Expect a louder, more chaotic version of the same underlying idea.
For the closest match in structure and tone, start with Enter the Gungeon. Nuclear Throne is our pick when you want runs to move faster, and Hades is where we'd send you for a much stronger story thread. Dead Cells suits a player who wants the item experimentation paired with platforming, and Risk of Rain 2 is the choice for chaotic, item-stacking runs with friends.